- Professor & Co-principle investigator
In Charge, Magnetoencephalography (MEG) Resource Facility to Treat Epilepsy (being commissioned as a National Facility) Dept of Biotechnology, Ministry of Science and Technology, India
Magnetoencephalography (MEG) Resource Facility
All India Institute of Medical Sciences
Email: saratpchandra3@gmail.com
About:
Dr Chandra is currently holding the post of Professor of Neurosurgery at the All India Institute of Medical Sciences. He is the PI and team leader for the prestigious Center for excellence in epilepsy, which is funded by Dept of Biotechnology (Ministry of Science and Technology, Govt of India). He has done his post doc fellowship from the reputed University California, Los Angles(UCLA).He also underwent multiple short term trainings from WakeForest University (Penry mini fellow, epilepsy), Cleveland clinic (spine) and Greifswald university (neuro endoscopy). He has now an experience of over 18,000 cases and has chief interest in epilepsy surgery (over 1000 cases), complex spine and cranio vertebral junction anomalies (4000 cases), vascular especially minimally invasive key approach to aneurysms (400 cases). His additional qualifications include being part of world faculty 1000 in the International League against epilepsy (ILAE), being as EC member of Indian epilepsy society, EC member of Neurological Society of India (NSI), EC member of Asian Epilepsy Surgery Society (AESC) and as member of sub commission of pediatric epilepsy surgery in the ILAE and founding editor-in-chief of Indian Journal of Neurosurgery (IJNS). He has delivered over 100 lectures in various conferences and has over 167 publications and 10 research projects.He has published 2 books and has 3 patents (2 developed and 1 in process with Medtronic), and organized numerous National and International conferences. He is also a member of National program for epilepsy control being developed by Ministry of Health and Family Welfare .
Funding :
| Research Projects | ||||
|---|---|---|---|---|
| Sno | Name of Project | Funding Agency, amount of funding | Year Of Completion | National/International |
| 1 | STICH I | Medical Research Council, UK, Rs 5 lakhs | 2003 | International (Co-PI) |
| 2 | Visuomotor control of eye movements | NBRC | 2008 | National (Co-PI) |
| 3 | ISS implantation for Vascular Dementia | BRAINSGATE, Israel, Rs 10 lakhs | 2009 | International (PI) |
| 4 | Autonomic functions in patients undergoing surgery for intractable epilepsy” | Dept of Science and Technology, India, Rs 17 lakhs | 2009 | National (Co-PI) |
| 5 | Differential expression of neurotransmitters from hippocampus during amygdalohippocampectomy for epilepsy surgery | Dept of Biotechnology, ministry of Science and Technology, India (Rs 30 lakhs) | 2010 | National (PI) |
| 6 | Evaluation of Autonomic function saccadic eye movement control and Fibrillin gene (Exon 24-28) | Dept of Biotechnology, ministry of Science and Technology, India (Rs 17 lakhs) | 2011 | National (PI) |
| 7 | STICH II | Medical Research Council, UK, Rs 10 lakhs | 2011 | International (PI) |
| 8 | STITCH | Medical Research Council, UK, Rs 6 lakhs | 2011 | International, Centre principal investigator (PI) and National coordinator |
| 9 | Assessment of mutations in GABRG2 gene from microelectrocorticographycally defined areas of hippocampus and amygdale in patients with MTLE with intractable epilepsy | Dept of Biotechnology, Ministry of Science and Technology, India (39 lakhs) | 2013 | National (PI) |
| 10 | Exon Defects in Osseous developmental CVJ anomalies | Dept of Biotechnology, Ministry of Science and Technology, India (17 lakhs) | 2011-continuing | National (PI) |
| 11 | fMRI and simultaneous EEG for localizing the epileptogenic focus in patients with intractable epilepsy | Dept of Biotechnology, ministry of Science and Technology, India (17 lakhs) | 2011-continuing | National (Co-PI) |
| 12 | Centre of Excellence to be commissioned as a National facility for difficult to treat epilepsy | Dept of Biotechnology,ministry of Science and Technology, India (40 crores). Collaborating centers AIIMS & NBRC | 2011-2017 | National Center of Excellence (PI and Team leader) |
| 13 | "Deciphering the role of casein kinase 2 in mesial temporal lobe epilepsy” | Dept of Science and Technology,India. | 2016-continuing | National |
| 14 | "Deciphering the role of Histone deacetylases (HDACs) in mesial temporal lobe epilepsy(MTLE)” | Intramural Grant AIIMS | 2016-continuing | National (CO-PI) |
| 15 | : "Role of kynurenic acid on hyperexcitability associated with mesial temporal lobe epilepsy” | Department of Science & Technology, India | 2017-continuing | National (PI) |
| 16 | : "Deciphering the role of GABA A receptor alterations in pediatric and adult patients with focal cortical Dysplasia” | Intramural grant AIIMS | 2017-continuing | National (CO-PI) |
| 17 | : "Deciphering the role of ATF3 and TGF? signaling in mesial temporal lobe epilepsy” | Intramural grant AIIMS | 2018-continuing | National (CO-PI) |
| 18 | : "Centre of Excellence for Epilepsy Phase II ” | by Dept of Biotechnology, ministry of Science and Technology, India | 2018-continuing | National (PI and Team Leader) |
Selected Publication:
| EPILEPSY: | |
|---|---|
| 1 | Ahmad FU, Tripathi M, Padma MV, Gaikwad S, Gupta A, Bal CS, Sarkar C, Gupta S, Wadhawan AN, Sharma BS, Chandra PS. Health-related quality of life using QOLIE-31: before and after epilepsy surgery a prospective study at a tertiary care center. Neurol India. 2007 Oct-Dec;55(4):343-8. PubMed PMID: 18040106. |
| 2 | Banerjee J, Chandra SP, Kurwale N, Tripathi M. Epileptogenic networks and drug-resistant epilepsy: Present and future perspectives of epilepsy research-Utility for the epileptologist and the epilepsy surgeon. Ann Indian Acad Neurol. 2014 Mar;17(Suppl 1):S134-40. doi: 10.4103/0972-2327.128688. PubMed PMID: 24791082; PubMed Central PMCID: PMC4001228. |
| 3 | Banerjee J, Tripathi M, Chandra PS. Understanding complexities of synaptic transmission in medically intractable seizures: A paradigm of epilepsy research. Indian J Neurosurg 2013;2:71-6. |
| 4 | Bindra A, Chouhan RS, Prabhakar H, Chandra PS, Tripathi M. Perioperative anesthetic implications of epilepsy surgery: a retrospective analysis. J Anesth. 2014 Oct 7. Nehra A, Singla S, Bajpai S, Malviya S, Padma V, Tripathi M. Inverse |
| 5 | Bindra A, Chouhan RS, Prabhakar H, Dash HH, Chandra PS, Tripathi M. Comparison of the effects of different anesthetic techniques on electrocorticography in patients undergoing epilepsy surgery - a bispectral index guided study. Seizure. 2012 Sep;21(7):501-7. doi: 10.1016/j.seizure.2012.05.002. Epub 2012 May 23. PubMed PMID: 22632798. |
| 6 | Chandra PS, Ansari A, Chauhan A, Kumar A, Garg A, Sarkar C. Surgery for encephalomalacias presenting with intractable epilepsy. Indian Journal of Neurosurgery, 2012, Jan 1(1): 33-37. |
| 7 | Chandra PS, Bal C, Garg A, Gaikwad S, Prasad K, Sharma BS, Sarkar C, Singh MB, Padma VM, Tripathi M. Surgery for medically intractable epilepsy due to postinfectious etiologies. Epilepsia. 2010 Jun;51(6):1097-100. doi: 10.1111/j.1528-1167.2010.02538.x. Epub 2010 Mar 18. PubMed PMID: 20345935. |
| 8 | Chandra PS, Bal CS, Jain S, Joshua SP, Gaikwad S, Garg A, Ansari A, Nehra A,Sarkar C, Tripathi M. Intra-Operative Co-Registration of MRI, PET andElectrocorticographic Data for Neocortical Lesional Epilepsies May Improve theLocalization of the Epileptogenic Focus: A Pilot Study. World Neurosurg. 2013 Feb |